For Full list of our

Recent Publications: 

Ferguson JW, Devarajan M, Atit RP. Stage-specific roles of Ezh2 and Retinoic acid signaling ensure calvarial bone lineage commitment. Dev Biol. 2018 Nov 15;443(2):173-187. 

DiNuoscio G., Atit RP. Wnt/beta-catenin signaling in the mouse embryonic cranial mesenchyme is required to sustain the emerging differentiated meningeal layers. Genesis 2019. Jan;57(1); e23279. doi:10.1002/dvg.23279


Ferguson JW, Atit RP. A tale of two cities: The genetic mechanisms governing calvarial bone development. Genesis. 2018 Aug 28:e23246. doi: 10.1002/dvg.23248. Review.

Other Publications from our lab:  

Ferguson J, Devarajan M, DiNuoscio G, Saiakhova A, Liu CF, Lefebvre V, Scacheri P, Atit RP. PRC2 is Dispensable in Vivo for β-Catenin-Mediated Repression of Chondrogenesis in Mouse Embryonic Cranial Mesenchyme. G3 (Bethesda). 2017 Dec 9. (Epub ahead of print). 

Mullin NK, Mallipeddi NV, Hamburg-Shields E, Ibarra B, Khalil AM, Atit RP.Wnt/β-catenin Signaling Pathway Regulates Specific lncRNAs That Impact Dermal Fibroblasts and Skin Fibrosis. 2017, Frontiers Genetics. Nov 21:8.   

Budnick I, Hamburg-Shields E, Chen, D., Torre, E, Jarrell A., Akhtar-Zaidi B, Cordovan O, Spitale RC, Scacheri PC, Atit RP. (2016). Defining the identity of mouse embryonic dermal fibroblasts. genesis: Journal of Genetics and Development 2016 Aug;54(8):415-30. 

Xiao Y, Thoresen DT, Williams JS, Atit RP, Wong SY, Brownell I. (2016). Sonic hedgehog signaling is essential for touch dome Merkel cell development. PLoS Genetics, 12 (7):e1006150.

Goodnough LH, DiNuoscio GJ, Radhika Atit (2016). Twist1 contributes to cranial bone initiation and dermal condensation by maintaining Wnt signaling responsiveness. Developmental Dynamics.  Feb;245(2):144-56.. 

Hamburg-Shields E, DiNuoscio GJ, Mullin NK, Lafayatis R, Radhika Atit (2015). Sustained beta-catenin activity in dermal fibroblasts promotes fibrosis by up-regulating expression of matrix protein-coding genes. J of Pathology, 235, p686-97.

Goodnough, L.H. DiNuoscio, G, Ferguson, J.W., Williams T., Lang R.A., and Radhika Atit (2014). Distinct requirements for cranial ectoderm and mesenchyme-derived Wnts in specification and differentiation of osteoblast and dermal progenitors. PLoS Genetics,  10, e1004152.

Goodnough LH, Chang AT, Treloar C, Yang J, Scacheri PC, Radhika Atit.(2012). Twist1 mediates repression of chondrogenesis by β-catenin to promote cranial bone progenitor specification. Development, 139, p. 4428-38.

Myung PS, Takeo M, Ito M, Radhika Atit.(2012). Epithelial Wnt ligand secretion is required for adult hair follicle growth and regeneration.Journal of Investigative Dermatology, 133, p31-41.

Emily Hamburg and Radhika Atit (2012). Sustained beta-catenin activity in dermal fibroblasts is sufficient for skin fibrosis, Journal of Investigative Dermatology, 132, p2469-72.

Demeng Chen, Andrew Jarrell, Canting Guo, Richard Lang, Radhika Atit (2012). Dermal beta-catenin in response to ectodermal Wnt ligands are required for fibroblast proliferation and hair follicle initiation, Development, 139: 1522-33.

Jun Wei, F. Fang, Ann P. Lam, J.L. Sargent, Emily Hamburg, M.E. Hinchcliff, C. Gottardi, Radhika Atit, M.L. Whitfield, J. Varga (2012). Wnt/beta-catenin signaling is hyperactived in systemic sclerosis and induces smad-dependent fibrotic responses in mesenchymal cells,Arthritis and Rheumatism, 64, p2734-45.

Thu Tran, Andrew Jarrell, Gabriel Zentner, Isaac Brownell, Peter Scacheri, Radhika Atit (2010). Role of canonical Wnt signaling/beta-catenin in cranial dermal development, Development, 137: 3973-84.

Preethi Mani, Andrew Jarrell, John Myers, Radhika Atit (2010). Visualizing canonical Wnt signaling during mouse craniofacial development. Developmental Dynamics, 239:354-63.

Knothe Tate, ML; Falls, TD; McBride, SH; Atit, R., Knothe, UR (2008). Mechanical modulation of osteochondroprogenitor cell fate. Int. J. Biochem Cell Biol. 40 (12): 27020-38. (Review).

Jennifer Ohtola, John Myers, Batool Akhtar-Zaidi, Diana Zuzindlak, Pooja Sandesara, Karen Yeh, Susan Mackem, and Radhika Atit (2008). Beta-Catenin has sequential roles in the survival and specification of ventral dermis. Development 135:2321-2329.

Liu F, Chu EY, Watt B, Zhang Y, Gallant NM, Andl T, Yang SH, Lu MM, Piccolo S, Schmidt-Ullrich R, Taketo MM, Morrisey EE, Atit R, Dlugosz AA, Millar SE. (2008). Wnt/beta-catenin signaling directs multiple stages of tooth morphogenesis. Developmental Biology  313 p210-24

Atit R., Sgaier, S. Mohammed, O., Taketo, M., Dufort, D., Joyner, A., Niswander, L., Conlon, R. (2006). Beta-catenin activity is necessary and sufficient for dorsal dermal fate specification. in mouse. Developmental Biology, 296, p164-176.  

Atit, R. , Conlon, R, and Niswander, L. (2003).  EGFR signaling patterns the feather array by promoting interbud fate. Developmental Cell  4  p231-40

Rizvi, T.A, Ling, B., Huang, Y., Sidani, A., Atit, R., Largaespada, D.A., Boissy, R.E., and Ratner, N. (2002). A novel cytokine pathway suppresses glial cell melanogenesis after injury to adult nerve. J. Neuroscience  22 p.9831-40

Sherman, LS., Atit, R., Rosenbaum, T., Cox, A.D., Ratner, N. (2000). Single cell Ras-GTP analysis reveals altered Ras activity in a subpopulation of neurofibroma Schwann cells but not fibroblasts. J Biol Chem., 275 p.30740-5.

Atit, R., Mitchell, K., Nguyen, L., Warshawksy, D., Ratner, N. (2000). The neurofibromatosis type 1 (Nf1) tumor suppressor is a modifier of carcinogen-induced pigmentation and papilloma formation in C57Bl/6 mice. Accepted at J. Invest. Dermatology, 114 p.1093-1100.

Atit, R., Crowe, M., Wenstrup, R., Greenhalgh, D., and Ratner, N. (1999). The Nf1, tumor suppressor gene is required for normal skin wound healing, fibroblast proliferation, and collagen deposition. J. Invest. Dermatology, 112 p.835-842.