39. Nguyen, H., C., Song, Y., Kumar, S., Liang, F. -S.* A customizable platform to integrate CAR and conditional expression of immunotherapeutics in T cells. Int. J. Mol. Sci. 2024, 25, 10568. Link
38. Zhou, C., Wagner, S., Liang, F. -S.* Induced Proximity Labeling and Editing for Epigenetic Research. Cell Chem. Biol. 2024. doi.org/10.1016/j.chembiol.2024.05.005. Link
37. Xu, Y., Wang, Y., Liang, F. -S.* Site-Specific m6A Erasing via Conditionally Stabilized CRISPR-Cas13b Editor. Angew. Chem. Int. Ed. 2023. doi.org/10.1002/anie.202309291. Link
36. Chen, J.,# Nguyen, H.,# Yang, M., Zeng, F., Xu, Hang, Liang, F. -S.,* Wang, W.* A Theranostic Abscisic Acid-based Molecular Glue. Chem. Sci. 2023, 14, 3377. Link
35. Xu, Y., Tian, N., Shi, H., Zhou, C., Wang, Y., Liang, F. -S.* A Split CRISPR/Cas13b System for Conditional RNA Regulation and Editing. J. Am. Chem. Soc. 2023, 145, 5561. Link
34. Liang, F. -S.* Xu, Y. RNA Epigenetics and Epitranscriptomics: The Emerging Gene Regulatory Landscape Through RNA Modifications. Encyclopedia of Cell Biology. Elsevier, 2023, 580. Link
33. Xu, Y.,# Wang, Y.,# Liang, F. -S.* A CRISPR-based Strategy for Temporally Controlled Site-Specific Editing of RNA Modifications. Bio-protoc. 2023, 13, e4607. Link
32. Xu, Y., Liang, F. -S.* On demand CRISPR-mediated RNA N6-Methyladenosine Editing. Genes & Diseases 2022, doi.org/10.1016/j.gendis.2022.05.019. Link
31. Bhattarai, U., Liang, F. -S.* MicroRNAs and Other Noncoding RNAs in Human Pathology. MicroRNA: From Bench to Bedside, Elsevier, 2022, 469. Link
30. Shi, H.,# Xu, Y.,# Tian, N., Yang, M., Liang, F. -S.* Inducible and Reversible RNA N6-Methyladenosine Editing. Nat. Commun. 2022, 13, 1958. Link
*Highlighted in CWRU Daily (Link) and Phys.org (Link).
29. Zhao, W.,# Xu, Y.,# Wang, Y., Gao, D., King, J., Xu, Y., Liang, F. -S.* Investigating crosstalk between H3K27 acetylation and H3K4 trimethylation in CRISPR/dCas‑based epigenome editing and gene activation. Sci. Rep. 2021, 11, 15912. Link
28. Zhao, W., Wang, Y., Liang, F. -S.* Chemical and light inducible epigenome editing. Int. J. Mol. Sci. 2020, 21, 998. Link
27. Bhattarai, U.,# Hsieh, W. -C.,# Yan, H., Guo, Z. -F., Shaikh, A. Y., Soltani, A., Song, Y., Ly, D. H.,* Liang, F. -S.* Bifunctional small molecule-oligonucleotide hybrid as microRNA inhibitor. Bioorg. Med. Chem. 2020, 28, 115394. Link
26. Yan, H., Liang, F. -S.* “miRNA inhibition by proximity-enabled Dicer inactivation” Methods. 2019, 167, 117. Link
25. Yan, H., Zhou, M., Bhattarai, U., Song, Y., Zheng, M., Cai, J.,* Liang, F. -S.* Cyclic peptidomimetics as inhibitor for miR-155 biogenesis. Mol. Pharm. 2019, 16, 914. Link
24. Zeng, G., Wang, Y., Bruchez, M., Liang, F. -S.* A Self-Reporting Chemically Induced Protein Proximity System Based on a Malachite Green Derivative and the L5** Fluorogen Activating Protein. Bioconjugate Chem. 2018, 29, 3010. Link
23. Yan, H., Bhattarai, U., Song, Y., Liang, F. -S.* Design, synthesis and activity of light deactivatable microRNA inhibitor. Bioorg. Chem. 2018, 80, 492. Link
22. Zhao, W., Nguyen, H, Zeng, G., Gao, D. Yan H., Liang, F-S.* “Chemically Induced Proximity System Engineered from the Plant Auxin Signaling Pathway” Chem. Sci. 2018, 9, 5822. Link
21. Gao, D., Liang, F-S.* “Chemical Inducible dCas9-guided Editing of H3K27 Acetylation in Mammalain Cells” Methods Mol. Biol. 2018, 1767, 429. Link
20. Chen, T.#, Gao, D.#, Zhang, R., Zeng, G.,Yan, H., Lim, E., Liang, F-S.* “Chemically Controlled Epigenome Editing Through an Inducible dCas9 System” J. Am. Chem. Soc. 2017, 139, 11337. Link
19. Yan, H., Bhattarai, U., Guo, Z., Liang, F. -S.* “Regulating miRNA-21 Biogenesis by Bi-functional Small Molecules” J. Am. Chem. Soc. 2017, 139, 4987. Link
18. Zeng, G.#, Li, H.#, Wei, Y., Xuan, W., Zhang, R., Breden, L. E., Wang, W.*, Liang, F. -S.* “Engineering Iron Responses in Mammalian Cells by Signal-Induced Protein Proximity” ACS Synth. Biol. 2017, 6, 921. Link
17. Xuan, W., Pan, R., Li, G., Cao, Y., Liang, F. -S., Liu, K.*, Wang, W.* “Reaction-based “off-on” fluorescent probe enabling detection of endogenous labile Fe2+ and imaging Zn2+-induced Fe2+ flux in living cells and elevated Fe2+ in ischemic stroke” Bioconjugate Chem. 2016, 27, 302. Link
16. Zeng, G., Xuan, W., Zhang, R., Wang, W., Liang, F. -S.* “Constructing de novo H2O2 Signaling via Induced Protein Proximity” ACS Chem. Biol. 2015, 10, 1404. Link
15. Wright, C. W., Guo, Z. -F, Liang, F. -S.* “Light control of cellular processes using photocaged abscisic acid” ChemBioChem, 2015,16, 254. Link
14. Guo, Z. -F., Zhang, R., Liang, F. -S.* “Facile Functionalization of FK506 for Biological Studies by the Thiol-Ene ‘Click’ Reaction”RSC Adv., 2014, 4, 11400. Link
13. Jin, Q., Liang, F. -S.* “Chemical Tools for Spatiotemporal Regulation of microRNAs” Org. Chem. Curr. Res. 2013, 2, e121. Link
12. Liang, F. -S., Crabtree, G. R. “Small Molecule Induced Proximity” Chembiomolecular Science: at the Frontier of Chemistry and Biology, 2012, 115. Link
11. Liang, F. -S., Ho, W. Q., Crabtree, G. R. “Engineering the ABA Plant Stress Pathway for Regulation of Induced Proximity” Sci. Signal. 2011, 4, rs2. Link
*Highlighted in: “Inducible Gene Expression in Mammals: Plants Add to the Menu” Sci. Signal. 2011, 4, pe13. Link; “ABA Remastered” Nat. Struct. Mol. Biol. 2011, 18, 403. Link
10. Liang, F. -S., Crabtree, G. R. “Developmental Biology: The Early Heart Remodelled” Nature 2009, 459, 654. Link
9. Liang, F. -S., Greenberg, W. A., Hammond, J. A., Hoffmann, J, Head, S. R., Wong, C. -H. “Evaluation of RNA Binding Specificity of Aminoglycosides with DNA Microarrays” Proc. Natl. Acad. Sci. U.S.A. 2006, 103, 12311. Link
8. Liang, F. -S., Brik, A., Lin, Y.-C., Elder, J. H., Wong, C. -H. “Epoxide Opening in Water for Rapid Inhibitor Discovery in Microtiter Plate and in situ Screening” Bioorg. Med. Chem. 2006, 14, 1058. Link
7. Fridman, M., Belakhov, V., Lee, L. V., Liang, F. -S., Wong, C. -H. & Baasov, T. “Dual Effect of Synthetic Aminoglycosides: Antibacterial Activity Against Bacillus anthracis and Inhibition of Anthrax Lethal Factor” Angew. Chem. Int. Ed. 2005, 44, 447. Link
6. Liang, F. -S., Wang, S.-K., Nakatani, T. & Wong, C. -H. “Targeting RNAs by Tobramycin Analogs” Angew. Chem. Int. Ed. 2004, 43, 6496. Link
5. Wu, C. -Y., Jan, J. -T., Ma, S. -H., Kuo, C. -J., Juan, H. -F., Cheng, Y. -S. E., Hsu, H. -H., Huang, H. -C., Wu, D., Brik, A., Liang, F. -S., Liu, R. -S., Fang, J. -M., Chen, S. -T., Liang, P. H., Wong, C. -H. “Small Molecules Targeting Severe Acute Respiratory Syndrome Human Coronavirus” Proc. Natl. Acad. Sci. U.S.A. 2004, 101, 10012. Link
4. Lee, L. V., Bower, K. E., Liang, F. -S., Shi, J., Wu, D., Sucheck, S. J., Vogt, P. K., Wong, C. -H. “Inhibition of the Proteolytic Activity of Anthrax Lethal Factor by Aminoglycosides” J. Am. Soc. Chem. 2004, 126, 4774. Link
3. Agnelli, F., Sucheck, S. J., Marby, K. A., Rabuka, D., Yao, S. -L., Sears, P. S., Liang, F. -S., Wong, C. -H. “Dimeric Aminoglycosides as Antibiotics” Angew. Chem. Int. Ed. 2004, 43, 1562. Link
2. Wong, C. -H., Liang, F. -S. “Surface Plasmon Resonance Study of RNA-Aminoglycoside Interactions” Methods Enzymol. 2003, 362, 340. Link
1. Ho, T. -L., Liang, F. -S. “Synthesis of ent-Herbasolide” Chem. Commun. 1996, 1887. Link