Parasitic organisms evolve to survive in numerous host environments. The parasitic schistosome worm is no exception, and is the cause of schistosomiasis, a global disease affecting over 200 million people across 76 countries. The schistosome lifecycle is characterized by remarkable phenotypic and genetic transitions between a molluscan host, a mammalian Schistosomehost, and a free swimming larva, and may live for up to 30 years. The transcriptional regulators involved in directing gene expression to control these diverse transformations are unknown. Our research focus is to identify key regulators of schistosome gene expression and their targets and determine the mechanism of transcriptional control in response to developmental and environmental cues.

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Caricature by former student, Nesreen Jawharti

Here is a lovely caricature of the Jolly Lab, drawn by former undergraduate student, Nesreen Jawharti. The picture depicts the members of the Jolly Lab riding a majestic cercaria. The lab members are from left to right: Anida Karahodza, Kenji Ishida, Melissa Varrecchia, Shuang Liang and Dr Emmitt Jolly.


Dr Jolly was recently highlighted in the Case Western Art-Sci magazine...


Dr Jolly and others were recently highlighted in Think Magazine.    

Jolly Lab Ski Trip with the Tolbert Lab

Pictures from the Jolly and Tolbert Labs Ski Trip to Holiday Valley in March 2015.    

Dr. Jolly Interviewed for Ohio TV and NPR

Dr. Jolly was interviewed for Ohio TV's weekly Science Cafe program in a segment titled Parasites. The video interview (above) is featured on Ohio TV's website; a National Public Radio broadcast is also available for listening and download here. It was followed by a Science Cafe in downtown...

Jolly Lab Featured In Case Daily

Dr. Emmitt Jolly and John Milligan were recently featured in the Case daily, a Case Western Reserve University publication, in an article titled "Researchers identify crucial gene activator in slow-killing parasite." The article discusses work recently published in the Public Library of Science Neglected Tropical Diseases (PLoS-NTDs), which featured...

Congratulations to our 2011 graduates

The Jolly Lab is pleased to announce our second graduating class this Spring consisting of three outstanding undergraduate students. Katherine Taylor (left), Stephanie Chinchen (center), and Tanvi Koht (right) all received their Bachelors of Science degrees in Biology on May 25th. Katherine plans on attending veterinary school next Fall,...

Student Shikha Tandon, Olympic athlete, trains at Case Shikha Tandon, a current master's student in our lab and former Olympic swimmer representing India, was recently featured in a promotional video for Case Western Reserve University. The video, featuring Shikha discussing her training at Case in both swimming and biology, can also be found here.

Congratulations to our Alumni

  Jolly Lab Graduates and year degree completed in lab Dr. Melissa Varrecchia, PhD 2017 Dr. Kenji Ishida, PhD 2017 Dr. Shuang Liang, PhD 2015 Anida Karahodza, MS 2015 Janay Jones, MS 2013 Shikha Tandon, MS 2012 Dr. Shadhi Malakooti, MS 2010 Dr Anna Lukic, MS 2010   Undergraduates Supervised in the Jolly Lab Dr. Jinny Ye        ...